منابع مشابه
Familial adenomatous polyposis coli.
The other mode of treating these patients are subtotal colectomy with ileorectal anastomosis alongwith regular follow up with proctoscopy for development of cancer in retained rectal mucosa(3,7). Recently, Stevan et al. (8) utilized laproscope for total proctocolectomy as well as ileoanal anostomosis while others performed ileopouch anal anastomosis alongwith total proctocolectomy(9,10). Thus t...
متن کاملFamilial Polyposis Coli
observations which they regard as established facts. For example: in discussing patients with temporal lobe epilepsy (TLE), the statement is made, "interictal aggressiveness is a common feature but is relatively well tolerated by many of the families, probably because of the marked emotional warmth customarily displayed by these same patients toward the family members." To illustrate these poin...
متن کاملThe Gene for Familial Polyposis Coli Maps
The inherited genetic defect in adenomatous polyposis has been localized to a small region on the long arm of chromosome 5. Sixteen DNA marker loci were used to construct a linkage map ofthe chromosome. When five kindreds segregating a gene for adenomatous polyposis coli were characterized with a number of the markers, significant linkage was found between one marker and the disease gene. Linka...
متن کاملFamilial polyposis coli and its extracolonic manifestations.
A detailed clinical study of 30 families with familial polyposis coli is presented. Seven 'isolated' cases are also described. It was found that some families did not exhibit any extracolonic manifestations, but the majority of families showed various numbers of members who had these manifestations of differing types and degrees. In view of the great variability within the members of a family, ...
متن کاملFamilial polyposis coli: heterogeneous polyp expression in 2 kindreds.
We describe 2 extended kindreds supposedly manifesting familial multiple adenomatous polyposis coli (FPC), but which show marked heterogeneity in the phenotypic expression of colorectal adenomatous polyps. In one family, 2 individuals had diffuse polyposis at very early ages (7 and 10 years), while 6 others (aged 23 to 72 years) had solitary polyps only. Of the patients with solitary polyps, 2 ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1976
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1976.146